| A highly specific BODIPY-based fluorescent probe for the detection of hypochlorous acid. | |
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MedLine Citation:
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PMID: 18447382 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A fluorescent probe, HKOCl-1, has been successfully developed for the detection of hypochlorous acid on the basis of a specific reaction with p-methoxyphenol. The formation of HOCl has been successfully detected not only in an abiotic system but also in an enzymatic system (myeloperoxidase/H2O2/Cl(-) system) and in living macrophage cells upon stimulation. This new probe might be used as an efficient tool for probing the roles HOCl plays in biological systems. |
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Authors:
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Zhen-Ning Sun; Feng-Qin Liu; Yan Chen; Paul Kwong Hang Tam; Dan Yang |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2008-05-01 |
Journal Detail:
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Title: Organic letters Volume: 10 ISSN: 1523-7060 ISO Abbreviation: Org. Lett. Publication Date: 2008 Jun |
Date Detail:
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Created Date: 2008-05-29 Completed Date: 2008-09-29 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100890393 Medline TA: Org Lett Country: United States |
Other Details:
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Languages: eng Pagination: 2171-4 Citation Subset: IM |
Affiliation:
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Department of Chemistry, The University of Hong Kong, Hong Kong, P.R. China. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Boron Compounds
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chemistry* Fluorescence Fluorescent Dyes / chemistry* Hypochlorous Acid / analysis*, chemistry* Substrate Specificity |
| Chemical | |
Reg. No./Substance:
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0/4,4-difluoro-4-bora-3a,4a-diaza-s-indacene; 0/Boron Compounds; 0/Fluorescent Dyes; 7790-92-3/Hypochlorous Acid |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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