Document Detail

A highly selective fluorescent probe for fast detection of hydrogen sulfide in aqueous solution and living cells.
MedLine Citation:
PMID:  23023578     Owner:  NLM     Status:  Publisher    
A new ratiometric fluorescence probe based on an excited-state intramolecular proton transfer (ESIPT) mechanism for detection of hydrogen sulfide (H(2)S) is reported. responds to H(2)S quickly and showed a 30-fold fluorescence enhancement in 2 minutes. Moreover, can detect H(2)S quantitatively with a detection limit as low as 0.12 μM in aqueous solution. Its potential for biological applications was confirmed by employing it for fluorescence imaging of H(2)S in living cells.
Zheng Xu; Lin Xu; Ji Zhou; Yufang Xu; Weiping Zhu; Xuhong Qian
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-10-1
Journal Detail:
Title:  Chemical communications (Cambridge, England)     Volume:  -     ISSN:  1364-548X     ISO Abbreviation:  Chem. Commun. (Camb.)     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2012-10-1     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9610838     Medline TA:  Chem Commun (Camb)     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Shanghai Key Laboratory of Chemical Biology, State Key Laboratory of Bioreactor Engineering, School of Pharmacy, East China University of Science and Technology, Shanghai, 200237, China.
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