Document Detail

A high-fat meal increases cardiovascular reactivity to psychological stress in healthy young adults.
MedLine Citation:
PMID:  17374657     Owner:  NLM     Status:  MEDLINE    
The consumption of high levels of saturated fat over the course of several weeks may lead to exaggerated cardiovascular reactivity. The consumption of a single high-fat meal has been associated with a transient impairment of vascular function. In a randomized, repeated measures, crossover study we tested whether the consumption of a single high-fat meal by healthy, normotensive participants would affect cardiovascular reactivity when compared with an isocaloric, low-fat meal. Thirty healthy participants ate a high-fat (42 g) and a low-fat (1 g) meal on 2 separate occasions, and their cardiovascular response to 2 standard laboratory stressors was measured. Systolic blood pressure, diastolic blood pressure, and total peripheral resistance were greater in participants following the consumption of the high-fat meal relative to the low-fat meal. The findings of the present study are consistent with the hypothesis that even a single high-fat meal may be associated with heightened cardiovascular reactivity to stress and offer insight into the pathways through which a high-fat diet may affect cardiovascular function.
Fabijana Jakulj; Kristin Zernicke; Simon L Bacon; Laura E van Wielingen; Brenda L Key; Sheila G West; Tavis S Campbell
Related Documents :
15023637 - Water settlement alters faeces composition and digestibilities of pink snapper diets.
3805467 - Relative value of solvent and expeller soybean meal for lactating dairy cows.
15640457 - Temporal pattern of de novo lipogenesis in the postprandial state in healthy men.
19759247 - Satiation due to equally palatable sweet and savory meals does not differ in normal wei...
22624117 - Preparation and evaluation of a novel therapeutic dairy-based drink for phenylketonuria.
9771337 - Calcium levels in maternal milk: relationships with calcium intake during the third tri...
Publication Detail:
Type:  Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  The Journal of nutrition     Volume:  137     ISSN:  0022-3166     ISO Abbreviation:  J. Nutr.     Publication Date:  2007 Apr 
Date Detail:
Created Date:  2007-03-21     Completed Date:  2007-05-04     Revised Date:  2007-11-20    
Medline Journal Info:
Nlm Unique ID:  0404243     Medline TA:  J Nutr     Country:  United States    
Other Details:
Languages:  eng     Pagination:  935-9     Citation Subset:  IM    
University of Calgary, Department of Psychology, Calgary, AB, Canada T2N 1N4.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Analysis of Variance
Blood Pressure / drug effects
Cardiovascular System / drug effects*,  physiopathology*
Cross-Over Studies
Dietary Fats / administration & dosage*,  pharmacology
Dose-Response Relationship, Drug
Stress, Psychological / physiopathology*
Vascular Resistance / drug effects
Reg. No./Substance:
0/Dietary Fats
Comment In:
J Nutr. 2007 Dec;137(12):2814; author reply 2815   [PMID:  18029505 ]
Obes Surg. 2007 Jul;17(7):856   [PMID:  17894141 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Associations of total, dairy, and meat protein with markers for bone turnover in healthy, prepuberta...
Next Document:  Quantitative NMR analysis of a sesamin catechol metabolite in human urine.