| A hemolysis trigger in glucose-6-phosphate dehydrogenase enzyme deficiency. Vicia sativa (Vetch). | |
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MedLine Citation:
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PMID: 19198723 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Glucose-6-phosphate dehydrogenase (G6PD) is an enzyme, playing an important role in the redox metabolism of all aerobic cells. It was reported that certain medications, fava beans, and infections can trigger acute hemolytic anemia in patients with G6PD deficiency. An 8-year-old male patient was admitted to the hospital with blood in the urine, headache, dizziness, fatigue, loss of appetite, and jaundice in the eyes, 24 hours after eating large amounts of fresh, vetch grains. Laboratory investigation revealed hemolytic anemia, hyperbilirubinemia, and G6PD deficiency. Approximately 0.5% of fava bean seeds have 2 pyrimidine beta-glycosides called, vicine and convicine. Vetch has 0.731% vicine, 0.081% convicine, and 0.530% beta cyanoalanine glycosides. The aim of this case report is to emphasize the importance of vetch seeds as a cause for hemolytic crisis in our country, where approximately one million tons of vetch is produced per year, especially in the agricultural regions. |
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Authors:
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Zafer Bicakci |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Saudi medical journal Volume: 30 ISSN: 0379-5284 ISO Abbreviation: Saudi Med J Publication Date: 2009 Feb |
Date Detail:
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Created Date: 2009-02-09 Completed Date: 2009-05-05 Revised Date: 2009-07-20 |
Medline Journal Info:
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Nlm Unique ID: 7909441 Medline TA: Saudi Med J Country: Saudi Arabia |
Other Details:
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Languages: eng Pagination: 292-4 Citation Subset: IM |
Affiliation:
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Department of Pediatrics, Kafkas University, Pasacayiri 36300, Kars, Turkey. zaferbicakcib@yahoo.com.tr |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Anemia, Hemolytic
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chemically induced* Child Glucosephosphate Dehydrogenase Deficiency / complications* Humans Male Vicia / poisoning* |
| Comments/Corrections | |
Comment In:
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Saudi Med J. 2009 Jul;30(7):974; author reply 974-5
[PMID:
19618021
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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