Document Detail

The hemodynamic significance of massive pneumopericardium in preterm infants with respiratory distress syndrome. Clinical and experimental observations.
MedLine Citation:
PMID:  386417     Owner:  NLM     Status:  MEDLINE    
Radiographic and clinical data were evaluated in 12 preterm infants with pneumopericardium complicating ventilator therapy of respiratory distress syndrome. Eight infants had massive or tension pneumopericardium, reflected by bradycardia, hypotension, and cyanosis of abrupt onset; cardiac size decreased dramatically but returned to approximately the former size after aspiration of the pneumopericardium. In puppies, pneumopericardium large enought to reduce heart size by 32 +/- 3% caused decreased mean arterial pressure (-22 +/- 7%) and right ventricular peak systolic pressure (-11 +/- 2%) and increased right ventricular diastolic and intrapericardial pressures. These findings suggest that pneumopericardium per se causes severe hemodynamic compromise. When it is large enought to reduce heart size, drastic circulatory impairment is produced and pericardiocentesis should be performed immediately.
C B Higgins; T W Broderick; D K Edwards; A Shumaker
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Radiology     Volume:  133     ISSN:  0033-8419     ISO Abbreviation:  Radiology     Publication Date:  1979 Nov 
Date Detail:
Created Date:  1979-12-18     Completed Date:  1979-12-18     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0401260     Medline TA:  Radiology     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  363-8     Citation Subset:  AIM; IM    
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MeSH Terms
Bradycardia / etiology
Cardiac Tamponade / etiology
Cyanosis / etiology
Heart / radiography
Hypotension / etiology
Infant, Newborn
Infant, Premature
Pneumopericardium / etiology*
Positive-Pressure Respiration / adverse effects*
Respiratory Distress Syndrome, Newborn / therapy*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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