| A helical PTFE arteriovenous access graft to swirl flow across the distal anastomosis: results of a preliminary clinical study. | |
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MedLine Citation:
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PMID: 17161962 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Intimal hyperplasia develops preferentially in regions where the blood flow is stagnant and wall shear stress low. The small amplitude helical geometry of the SwirlGraft was designed to ensure physiological-type swirling flow, and thus suppress the triggers. We report the first conceptual testing of the SwirlGraft. Primary, assisted primary and secondary patency rates at 6 months in 20 patients were 57.9+/-11.4%, 84.4+/-8.3% and 100+/-0.0%. There was angiographic evidence of reduction of helical geometry in a proportion of the grafts. The helical graft is associated with high assisted primary and secondary patency. Elaboration of the surgical implantation techniques and an improved SwirlGraft design can be expected to exploit the advantages of the helical concept. |
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Authors:
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H J T A M Huijbregts; P J Blankestijn; C G Caro; N J W Cheshire; M T C Hoedt; R P Tutein Nolthenius; F L Moll |
Publication Detail:
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Type: Clinical Trial; Journal Article; Multicenter Study Date: 2006-12-11 |
Journal Detail:
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Title: European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery Volume: 33 ISSN: 1078-5884 ISO Abbreviation: Eur J Vasc Endovasc Surg Publication Date: 2007 Apr |
Date Detail:
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Created Date: 2007-03-09 Completed Date: 2007-05-04 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9512728 Medline TA: Eur J Vasc Endovasc Surg Country: England |
Other Details:
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Languages: eng Pagination: 472-5 Citation Subset: IM |
Affiliation:
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Department of Vascular Surgery, University Medical Center Utrecht, Utrecht, The Netherlands. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aged, 80 and over Angiography Arm / blood supply* Arteriovenous Shunt, Surgical / adverse effects, instrumentation* Blood Vessel Prosthesis Implantation / adverse effects, instrumentation* Constriction, Pathologic / etiology Europe Female Follow-Up Studies Humans Male Middle Aged Pilot Projects Polytetrafluoroethylene* Prospective Studies Prosthesis Design Regional Blood Flow Renal Dialysis / methods* Thrombosis / etiology Time Factors Treatment Outcome Vascular Patency |
| Chemical | |
Reg. No./Substance:
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9002-84-0/Polytetrafluoroethylene |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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