Document Detail


The heart in uremia: role of hypertension, hypotension, and sleep apnea.
MedLine Citation:
PMID:  11576920     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Cardiovascular disease is the leading cause of morbidity and mortality in end-stage renal disease. Causes include those usually found in the general population, those related to the uremic status, and those related to dialytic treatment. Hypertension, hypotension, anemia, hypoalbuminemia, malnutrition, dyslipidemia, reactive C protein, calcium-phosphate product, dialysis modalities, and hyperhomocysteinemia are discussed extensively. Special emphasis is put on hyperparathyroidism as a traditional toxin. The emergent role of sleep apnea has been confirmed in animal models as well as in humans studied using polysomnography. There are difficulties in diagnosing coronary disease, because angiography is not risk-free, is expensive, and should be reserved for patients having symptoms of heart failure and/or patients having diabetes mellitus, and/or patients entering a transplantation list. This allows patients with coronary disease to undergo coronary artery bypass (preferably) or percutaneous transluminal angioplasty. Patients for whom surgery is not appropriate should be treated using more traditional medical procedures.
Authors:
N G De Santo; M Cirillo; A Perna; L S De Santo; P Anastasio; M R Pollastro; R M De Santo; L Iorio; M Cotrufo; F Rossi
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  American journal of kidney diseases : the official journal of the National Kidney Foundation     Volume:  38     ISSN:  1523-6838     ISO Abbreviation:  Am. J. Kidney Dis.     Publication Date:  2001 Oct 
Date Detail:
Created Date:  2001-09-28     Completed Date:  2001-12-04     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8110075     Medline TA:  Am J Kidney Dis     Country:  United States    
Other Details:
Languages:  eng     Pagination:  S38-46     Citation Subset:  IM    
Affiliation:
Chairs of Nephrology, Heart Surgery, Pharmacology, and Excellency Center for Heart Failure at the Second University of Naples, Naples, Italy.
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MeSH Terms
Descriptor/Qualifier:
Adult
Age Distribution
Aged
Cardiovascular Diseases / diagnosis,  epidemiology*,  physiopathology,  therapy
Comorbidity
Coronary Angiography
Coronary Disease / diagnosis,  epidemiology,  therapy
Female
Heart Failure / epidemiology
Heart Function Tests
Humans
Hypertension / epidemiology
Hypotension / epidemiology
Male
Middle Aged
Myocardial Revascularization
Prevalence
Renal Dialysis / statistics & numerical data
Risk Factors
Sex Distribution
Sleep Apnea Syndromes / etiology
Survival Rate
Uremia / epidemiology*,  therapy

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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