Document Detail

The heart in dermatomyositis and polymyositis.
MedLine Citation:
PMID:  16980718     Owner:  NLM     Status:  MEDLINE    
Cardiovascular manifestations constitute a major cause of death in myositis. Despite this, clinically manifest cardiac involvement in polymyositis and dermatomyositis is relatively rare. In contrast, subclinical manifestations are frequently reported and are predominated by conduction abnormalities and arrhythmias detected by ECG. The most frequently reported clinically overt manifestations are congestive heart failure, conduction abnormalities, that may lead to complete heart block, and coronary artery disease. The underlying pathophysiological mechanisms that may cause cardiac manifestations involve myocarditis and coronary artery disease as well as involvement of the small vessels of the myocardium.
I E Lundberg
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Rheumatology (Oxford, England)     Volume:  45 Suppl 4     ISSN:  1462-0332     ISO Abbreviation:  Rheumatology (Oxford)     Publication Date:  2006 Oct 
Date Detail:
Created Date:  2006-09-18     Completed Date:  2007-11-13     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  100883501     Medline TA:  Rheumatology (Oxford)     Country:  England    
Other Details:
Languages:  eng     Pagination:  iv18-21     Citation Subset:  AIM; IM    
Rheumatology Unit, Department of Medicine, Karolinska Institutet at Karolinska University Hospital, Solna Stockholm, Sweden.
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MeSH Terms
Cause of Death
Coronary Artery Disease / etiology,  mortality,  pathology
Dermatomyositis / complications,  mortality,  pathology*
Heart Diseases / etiology,  mortality,  pathology*
Myocarditis / etiology,  mortality,  pathology
Polymyositis / complications,  mortality,  pathology*

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