| The hard cell: from proteomics to a whole cell model. | |
| | |
MedLine Citation:
|
PMID: 17555749 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Proteomics has provided a wealth of data related to the nature of the proteome, including subcellular location, copy number, interaction partners and protein complexes. This raises the question of whether it is feasible to combine these data, together with other data related to overall cellular structure, to construct a static picture of the cell. In this minireview, we discuss these data, and the issues of turning them into whole cell models. |
| | |
Authors:
|
Matthew J Betts; Robert B Russell |
Related Documents
:
|
17874069 - Quantitative analysis of liver gst-p foci promoted by a chemical mixture of hexachlorob... 20648969 - Investigating the link between epithelial-mesenchymal transition and the cancer stem ce... 21095109 - Genistein effects on haematoimmune cells in a newly developed alternative toxicological... 18581299 - Unsteady-state operation of continuous fermentor for enhancement of cell mass production. 9039059 - Analysis and modeling of the primary cilium bending response to fluid shear. 17946779 - A data-driven computational model of the erbb receptor signaling network. 21519949 - Genotype-, aging-dependent abnormal caspase activity in huntington disease blood cells. 1083379 - Defective repair of gamma-ray induced dna damage in xeroderma pigmentosum cells. 20399 - Pathogenesis of cryptorchidism. |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't; Review Date: 2007-05-30 |
Journal Detail:
|
Title: FEBS letters Volume: 581 ISSN: 0014-5793 ISO Abbreviation: FEBS Lett. Publication Date: 2007 Jun |
Date Detail:
|
Created Date: 2007-06-11 Completed Date: 2007-08-30 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0155157 Medline TA: FEBS Lett Country: Netherlands |
Other Details:
|
Languages: eng Pagination: 2870-6 Citation Subset: IM |
Affiliation:
|
Structural and Computational Biology Unit, European Molecular Biology Laboratory, Meyerhofstrasse 1, 69117 Heidelberg, Germany. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Cells
/
metabolism* Genomics Humans Models, Biological* Multiprotein Complexes Proteomics* Two-Hybrid System Techniques |
| Chemical | |
Reg. No./Substance:
|
0/Multiprotein Complexes |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Isolation and characterization of nudC from mouse macrophages, a gene implicated in the inflammatory...
Next Document: Progesterone rise on the day of human chorionic gonadotropin administration impairs pregnancy outcom...