| The hand-foot-syndrome associated with medical tumor therapy - classification and management. | |
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MedLine Citation:
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PMID: 20482685 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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The hand-foot-syndrome (HFS, palmoplantar erythrodysesthesia, chemotherapy-associated acral erythema) is characterized by painful predominantly palmo-plantar lesions. The association with different chemotherapeutic agents has been known for over 20 years. More recently, HFS has been reported in association with regimens using targeted agents, in particular the multikinase inhibitors (MKI) sorafenib and sunitinib. The HFS associated with MKI has a different distribution and clinical appearance than the traditional disorder. In this review, similarities and differences between chemotherapy- and MKI-associated HFS are discussed and current recommendations for their prophylaxis and management are summarized. |
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Authors:
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Annette Degen; Mareike Alter; Florian Schenck; Imke Satzger; Bernward Völker; Alexander Kapp; Ralf Gutzmer |
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Publication Detail:
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Type: Journal Article Date: 2010-05-06 |
Journal Detail:
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Title: Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG Volume: 8 ISSN: 1610-0387 ISO Abbreviation: J Dtsch Dermatol Ges Publication Date: 2010 Sep |
Date Detail:
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Created Date: 2010-08-26 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101164708 Medline TA: J Dtsch Dermatol Ges Country: Germany |
Other Details:
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Languages: eng; ger Pagination: 652-61 Citation Subset: IM |
Affiliation:
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Clinic and Polyclinic for Dermatology, and Allergy, Skin Cancer Center Hannover (HTZH), Hannover Medical School, Germany. |
Export Citation:
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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