Document Detail


Is half-dose contrast-enhanced three-dimensional MR angiography sufficient for the abdominal aorta and pelvis?
MedLine Citation:
PMID:  14745753     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: To evaluate the usefulness of half-dose contrast-enhanced magnetic resonance (MR) angiography for depicting the abdominal aorta and its major branches. MATERIALS AND METHODS: A total of 72 consecutive patients were randomly assigned to one of four groups that underwent MR angiography after receiving different concentrations (original or diluted to 50%) and total amounts (single or half-dose) of gadolinium chelate injected at different rates (1 or 0.5 mL/second). The signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) of the abdominal aorta and of the common and external iliac arteries were calculated, and two blinded readers rated the respective image qualities. RESULTS: The SNR and CNR of the abdominal aorta and the common iliac artery in the 0.5 mL/second groups were statistically significantly lower than those in the 1 mL/second groups. The differences in overall image quality across the four groups were not statistically significant. CONCLUSION: Half-dose MR angiography using diluted contrast medium injected at a rate of 1 mL/second depicted the abdominal aorta and its branches as clearly as using a full single dose.
Authors:
Satoru Takahashi; Takamichi Murakami; Manabu Takamura; Tonsok Kim; Masatoshi Hori; Yoshifumi Narumi; Hironobu Nakamura
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Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Journal of magnetic resonance imaging : JMRI     Volume:  19     ISSN:  1053-1807     ISO Abbreviation:  J Magn Reson Imaging     Publication Date:  2004 Feb 
Date Detail:
Created Date:  2004-01-27     Completed Date:  2004-06-23     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9105850     Medline TA:  J Magn Reson Imaging     Country:  United States    
Other Details:
Languages:  eng     Pagination:  194-201     Citation Subset:  IM    
Copyright Information:
Copyright 2004 Wiley-Liss, Inc.
Affiliation:
Department of Clinical Informative Imagiology, Osaka University Graduate School of Medicine, Osaka, Japan. takahashi@inf-img.med.osaka-u.ac.jp
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MeSH Terms
Descriptor/Qualifier:
Analysis of Variance
Aorta, Abdominal / anatomy & histology*
Contrast Media / administration & dosage
Dose-Response Relationship, Drug
Female
Gadolinium DTPA / administration & dosage,  diagnostic use*
Humans
Imaging, Three-Dimensional / methods*
Injections, Intravenous
Magnetic Resonance Angiography / methods*
Middle Aged
Pelvis / anatomy & histology*,  blood supply
Phantoms, Imaging
Statistics, Nonparametric
Chemical
Reg. No./Substance:
0/Contrast Media; 80529-93-7/Gadolinium DTPA

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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