| The haemodynamics of the distal arterial Y-shaped autograft bypass-flap in a porcine experimental model. | |
| | |
MedLine Citation:
|
PMID: 18922708 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
BACKGROUND: The haemodynamic effects of revascularisation with combined bypass and free-muscle flap remain controversial. In a porcine experimental model, we investigated the transplantation-induced changes in the haemodynamics of a Y-shaped combined arterial autograft bypass-muscle flap (AABF). METHODS: Anatomy of AABF was identified in eight dissections in four porcine cadavers. In five animals, AABF served as a superficial femoral artery (SFA) defect replacement. Modelled, triggered pulsatile pressure (P) and flow (Q) waves delivered mean haemodynamics and PQ hysteresis loops before and after transplantation at days 0 and 10. RESULTS: Anatomically, AABF combined subscapular and circumflex-scapular arteries, and thoracodorsal artery as latissimus dorsi flap pedicle. Surgical feasibility and AABF patency were confirmed in each case. At day 0, the proximal flow was increased in the grafted Y-shaped AABF, which also adopted the specific SFA pulsatile haemodynamics. Regulatory mechanisms of AABF vasomotricity were preserved and AABF-flow-dependence amplified the flow in the distal segment, which otherwise preserved its own flow dependence. At 10 days, the AABF flow was unchanged in the distal segment, and remained elevated in the proximal and pedicle segments. CONCLUSIONS: Combined AABF, as a single one-piece arterial autograft, was shown highly adaptive to the receiving arteries. The transplantation-induced changes in AABF pulsatile flow profile and vascular reactivity improve the overall graft flow, and strongly advocate for beneficial effects on the blood propelling capacity of the grafted circulation. |
| | |
Authors:
|
S Malikov; P H Rolland; P E Magnan; M Bartoli; P Champsaur; A Branchereau |
Related Documents
:
|
7881368 - Input impedance of radiocephalic arteriovenous fistulae for haemodialysis access: its v... 12638668 - Comparison of intraoperative transit-time flow measurement with early postoperative mag... 1622058 - Effect of perivascular sympathectomy on distal blood flow in the rabbit forepaw. a dyna... 3294848 - Blood flow measurement in ptfe grafts. 3877288 - Haematological and biochemical changes during anaesthesia with propofol ('diprivan'). 17365428 - A re-evaluation of modelling of the current flow between electrodes: consideration of b... |
Publication Detail:
|
Type: Journal Article Date: 2008-10-14 |
Journal Detail:
|
Title: European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery Volume: 37 ISSN: 1532-2165 ISO Abbreviation: Eur J Vasc Endovasc Surg Publication Date: 2009 Jan |
Date Detail:
|
Created Date: 2008-12-05 Completed Date: 2008-12-29 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9512728 Medline TA: Eur J Vasc Endovasc Surg Country: England |
Other Details:
|
Languages: eng Pagination: 77-84 Citation Subset: IM |
Affiliation:
|
Department of Vascular Surgery, School of Medicine, Mediterranean Sea University, La Timone Hospital, Marseilles, France. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Blood Vessel Prosthesis Implantation* Femoral Artery / surgery* Hemodynamics Ischemia / surgery* Lower Extremity / blood supply* Models, Animal Surgical Flaps* Swine Transplantation, Autologous* |
| Comments/Corrections | |
Comment In:
|
Eur J Vasc Endovasc Surg. 2009 Jan;37(1):85-6
[PMID:
19056061
]
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: A novel endovascular technique for exclusion of inner curve aortic arch aneurysm.
Next Document: Predicting risk in elective abdominal aortic aneurysm repair: a systematic review of current evidenc...