Document Detail


The gut hormones in appetite regulation.
MedLine Citation:
PMID:  21949903     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
Obesity has received much attention worldwide in association with an increased risk of cardiovascular diseases, diabetes, and cancer. At present, bariatric surgery is the only effective treatment for obesity in which long-term weight loss is achieved in patients. By contrast, pharmacological interventions for obesity are usually followed by weight regain. Although the exact mechanisms of long-term weight loss following bariatric surgery are yet to be fully elucidated, several gut hormones have been implicated. Gut hormones play a critical role in relaying signals of nutritional and energy status from the gut to the central nervous system, in order to regulate food intake. Cholecystokinin, peptide YY, pancreatic polypeptide, glucagon-like peptide-1, and oxyntomodulin act through distinct yet synergistic mechanisms to suppress appetite, whereas ghrelin stimulates food intake. Here, we discuss the role of gut hormones in the regulation of food intake and body weight.
Authors:
Keisuke Suzuki; Channa N Jayasena; Stephen R Bloom
Related Documents :
3086823 - Gastrin in the mechanisms of genetic determination of feeding behavior in rabbits.
18530123 - Passive acoustic localization techniques of eastern pacific grey whales.
15261403 - Concentrations of organotin compounds in sediment and clams collected from coastal area...
Publication Detail:
Type:  Journal Article     Date:  2011-09-22
Journal Detail:
Title:  Journal of obesity     Volume:  2011     ISSN:  2090-0716     ISO Abbreviation:  J Obes     Publication Date:  2011  
Date Detail:
Created Date:  2011-09-28     Completed Date:  2011-11-10     Revised Date:  2014-02-20    
Medline Journal Info:
Nlm Unique ID:  101526295     Medline TA:  J Obes     Country:  United States    
Other Details:
Languages:  eng     Pagination:  528401     Citation Subset:  -    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Grant Support
ID/Acronym/Agency:
G7811974//Medical Research Council
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Antihypertensive Treatment in the Elderly and Very Elderly: Always "the Lower, the Better?".
Next Document:  Multimodal MRI neuroimaging biomarkers for cognitive normal adults, amnestic mild cognitive impairme...