Document Detail

Is grip strength a useful single marker of frailty?
MedLine Citation:
PMID:  14600007     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: chronological age is widely used as a marker of frailty in clinical practice. However there can be wide variation in frailty between individuals of a similar age. Grip strength is a powerful predictor of disability, morbidity and mortality which has been used in a number of frailty scores but not as a single marker of frailty.
OBJECTIVE: to investigate the potential of grip strength as a single marker of frailty in older people of similar chronological age.
DESIGN: cross-sectional study with prospective collection of mortality data.
SETTING: North Hertfordshire, UK.
SUBJECTS: 717 men and women, aged 64-74, born and still living in North Hertfordshire, who took part in a previous study to investigate the relationship between size at birth and ageing processes in later life.
METHODS: the number of significant associations between grip strength and the ageing markers was compared with numbers between chronological age and the ageing markers.
RESULTS: in men, lower grip strength correlated significantly with ten ageing markers compared to chronological age which was significantly associated with seven. In women, there were six significant relationships for grip compared to three for age. The greater number of relationships between grip strength and ageing markers was not explained by the association between grip strength and age, and remained after adjustment for adult size.
CONCLUSIONS: grip strength was associated with more markers of frailty than chronological age within the narrow age range studied. Grip strength may prove a more useful single marker of frailty for older people of similar age than chronological age alone. Its validity in a clinical setting needs to be tested.
Holly Syddall; Cyrus Cooper; Finbarr Martin; Roger Briggs; Avan Aihie Sayer
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Age and ageing     Volume:  32     ISSN:  0002-0729     ISO Abbreviation:  Age Ageing     Publication Date:  2003 Nov 
Date Detail:
Created Date:  2003-11-05     Completed Date:  2004-04-21     Revised Date:  2013-04-29    
Medline Journal Info:
Nlm Unique ID:  0375655     Medline TA:  Age Ageing     Country:  England    
Other Details:
Languages:  eng     Pagination:  650-6     Citation Subset:  IM    
MRC Environmental Epidemiology Unit, University of Southampton, Southampton, UK.
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MeSH Terms
Cross-Sectional Studies
Disability Evaluation
Frail Elderly / statistics & numerical data*
Geriatric Assessment* / statistics & numerical data*
Hand Strength*
Predictive Value of Tests
Prospective Studies
Sex Factors
Statistics as Topic
Survival Analysis
Grant Support
MC_U147574239//Medical Research Council; U.1475.00.003.00010.02(74239)//Medical Research Council

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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