Document Detail

A gonadotropin-releasing hormone analogue impairs glucose tolerance in a diabetic patient.
MedLine Citation:
PMID:  9481560     Owner:  NLM     Status:  MEDLINE    
Changes in serum glucose levels were examined in a female with insulin-independent diabetes who received a gonadotropin-releasing hormone (GnRH) analog treatment for pelvic endometriosis. The mean blood glucose levels were higher on busereline therapy, and higher levels of hemoglobin A1c were noted on busereline therapy (range 6.9-12.5%) versus pre- and post-treatment (range 5.1-5.9%). Hormonal alteration induced by GnRH analog treatment may impair glucose tolerance.
A Imai; A Takagi; S Horibe; T Fuseya; H Takagi; T Tamaya
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  European journal of obstetrics, gynecology, and reproductive biology     Volume:  76     ISSN:  0301-2115     ISO Abbreviation:  Eur. J. Obstet. Gynecol. Reprod. Biol.     Publication Date:  1998 Jan 
Date Detail:
Created Date:  1998-04-01     Completed Date:  1998-04-01     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0375672     Medline TA:  Eur J Obstet Gynecol Reprod Biol     Country:  IRELAND    
Other Details:
Languages:  eng     Pagination:  121-2     Citation Subset:  IM    
Department of Obstetrics and Gynecology, Gifu University School of Medicine, Japan.
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MeSH Terms
Blood Glucose / metabolism*
Buserelin / adverse effects*,  therapeutic use
Danazol / therapeutic use
Diabetes Mellitus, Type 1 / blood,  complications*
Endometriosis / complications,  drug therapy*
Estrogen Antagonists / therapeutic use
Hemoglobin A, Glycosylated / metabolism
Reg. No./Substance:
0/Blood Glucose; 0/Estrogen Antagonists; 0/Hemoglobin A, Glycosylated; 17230-88-5/Danazol; 57982-77-1/Buserelin

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