| A goitrogenic agent from millet (Pennisetum typhoides) in Darfur Province, Western Sudan. | |
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MedLine Citation:
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PMID: 6830139 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Serum samples from girls from an elementary school in Western Sudan with grades O, I and II/III goitre were examined for their thiocyanate, cysteine, thyroxine, TSH and T3 concentrations. The concentrations of thiocyanate in all girls was higher than that reported in the literature for Nigerians, but the concentrations of thiocyanate were nevertheless significantly elevated, and those of thyroxine significantly lowered in girls with grades I and II/III goitre as compared with grade O. There were no significant differences between any of the groups in the concentrations of cysteine or TSH and T3. The predominant staple food eaten in this area of Sudan is millet and evidence is produced that this contains a goitrogenic thionamide which could be a factor in causing the endemic goitre. |
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Authors:
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A K Osman; T K Basu; J W Dickerson |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Annals of nutrition & metabolism Volume: 27 ISSN: 0250-6807 ISO Abbreviation: Ann. Nutr. Metab. Publication Date: 1983 |
Date Detail:
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Created Date: 1983-04-15 Completed Date: 1983-04-15 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8105511 Medline TA: Ann Nutr Metab Country: SWITZERLAND |
Other Details:
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Languages: eng Pagination: 14-8 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Cereals
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adverse effects* Child Female Goiter, Endemic / chemically induced, etiology* Humans Isothiocyanates* Panicum / adverse effects* Spectrophotometry, Ultraviolet Thiocyanates / blood Thyrotropin / blood Thyroxine / blood Triiodothyronine / blood |
| Chemical | |
Reg. No./Substance:
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0/Isothiocyanates; 0/Thiocyanates; 3129-90-6/isothiocyanic acid; 6893-02-3/Triiodothyronine; 7488-70-2/Thyroxine; 9002-71-5/Thyrotropin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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