| Is glycyrrhizin sensitivity increased in anorexia nervosa and should licorice be avoided? Case report and review of the literature. | |
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MedLine Citation:
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PMID: 20739148 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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OBJECTIVE: Hypokalemia is a potentially life-threatening electrolyte disturbance in anorexia nervosa and is most frequently caused by purging behavior. We report a case of severe hypokalemia in anorexia nervosa induced by daily ingestion of approximately 20 g of licorice. METHODS: To confirm the diagnosis of licorice-induced pseudohyperaldosteronism, a re-exposure trial was performed. RESULTS: Cessation of the licorice intake normalized plasma potassium, renin, and aldosterone levels and the urine cortisol/cortisone ratio. Re-exposure confirmed the diagnosis. The pronounced response to a relatively low daily dose of licorice suggests high glycyrrhizin sensitivity. CONCLUSION: Patients with anorexia nervosa not only have decreased food intake but also selective and sometimes bizarre eating habits that, in association with increased sensitivity to glycyrrhizin, may cause severe hypokalemia. |
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Authors:
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René K Støving; Linnéa E Lingqvist; Rasmus K Bonde; Alin Andries; Marianne H Hansen; Marianne Andersen; Kirsten Hørder |
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Publication Detail:
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Type: Journal Article Date: 2010-08-24 |
Journal Detail:
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Title: Nutrition (Burbank, Los Angeles County, Calif.) Volume: 27 ISSN: 1873-1244 ISO Abbreviation: Nutrition Publication Date: 2011 Jul-Aug |
Date Detail:
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Created Date: 2011-06-17 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8802712 Medline TA: Nutrition Country: United States |
Other Details:
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Languages: eng Pagination: 855-8 Citation Subset: IM |
Copyright Information:
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Copyright © 2011 Elsevier Inc. All rights reserved. |
Affiliation:
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Center for Eating Disorders and Department of Endocrinology, Odense University Hospital, Denmark University of Southern Denmark, Odense, Denmark. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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