Document Detail


A glucose-responsive controlled release of insulin system based on enzyme multilayers-coated mesoporous silica particles.
MedLine Citation:
PMID:  21779606     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
A novel glucose-responsive controlled release of insulin system is constructed through coating enzyme multilayers on mesoporous silica particles (MSPs). The MSPs serve as the drug reservoir, and the enzyme multilayers cross-linked with glutaraldehyde act as a valve to control the release of insulin in response to the external glucose level.
Authors:
Wenru Zhao; Hongti Zhang; Qianjun He; Yongsheng Li; Jinlou Gu; Liang Li; Hua Li; Jianlin Shi
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-7-22
Journal Detail:
Title:  Chemical communications (Cambridge, England)     Volume:  -     ISSN:  1364-548X     ISO Abbreviation:  -     Publication Date:  2011 Jul 
Date Detail:
Created Date:  2011-7-22     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9610838     Medline TA:  Chem Commun (Camb)     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Advanced Functional Materials Laboratory, School of Materials Science and Engineering, East China University of Science and Technology, Shanghai 20023, 7, China. wenruru@ecust.edu.cn.
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