| The glucose and insulin response to isoenergetic reduction of dietary energy sources in a true carnivore: the domestic cat ( Felis catus). | |
| | |
MedLine Citation:
|
PMID: 20193098 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The present study assessed the effect of separate reduction of each energy-delivering nutrient - protein, fat and carbohydrate - on glucose tolerance and insulin response in a strict carnivore: the domestic cat (Felis catus). Three isoenergetic, home-made diets with the following energetic distribution, low protein (LP): protein 28 % of metabolisable energy; fat 43 %; nitrogen-free extract 29 %; low fat: 47, 27 and 25 %; low carbohydrate (LC): 45, 48 and 7 %, were tested in a 3 x 3 Latin square design. Nine healthy normal-weight cats were randomly assigned to each of the diets in a random order at intervals of 3 weeks. At the end of each testing period, intravenous glucose tolerance tests were performed. Plasma glucose concentrations and area under the glucose curve showed no differences. Area under the insulin curve was lower when cats were fed the LP diet, and the second insulin peak tended to be delayed when the LC diet was fed. In contrast to other studies, in which energy sources were elevated instead of being reduced, the present trial contradicts the often suggested negative impact of carbohydrates on insulin sensitivity in carnivores, and shows that reducing the dietary carbohydrate content below common amounts for commercial foods evokes an insulin-resistant state, which can be explained by the cats' strict carnivorous nature. It even points to a negative effect of protein on insulin sensitivity, a finding that corresponds with the highly gluconeogenic nature of amino acids in strict carnivores. |
| | |
Authors:
|
Adronie Verbrugghe; Myriam Hesta; Stephanie Van Weyenberg; Georgios A Papadopoulos; Kris Gommeren; Sylvie Daminet; Tim Bosmans; Ingeborgh Polis; Johan Buyse; Geert P J Janssens |
Related Documents
:
|
7229358 - Diet and the diabetic: the fallacy of a controlled carbohydrate intake. 3637618 - The unique merits of a low-fat diet for weight control. 18635428 - Weight loss with a low-carbohydrate, mediterranean, or low-fat diet. 6651418 - Normal cardiac rhythm during hypocaloric diets of varying carbohydrate content. 6405578 - Effects of post-weaning malnutrition on the weight of the head components in rats. 886378 - Determination of the optimum dietary proportions of lysine and tryptophan for growing p... |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2010-03-02 |
Journal Detail:
|
Title: The British journal of nutrition Volume: 104 ISSN: 1475-2662 ISO Abbreviation: Br. J. Nutr. Publication Date: 2010 Jul |
Date Detail:
|
Created Date: 2010-07-14 Completed Date: 2010-08-09 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0372547 Medline TA: Br J Nutr Country: England |
Other Details:
|
Languages: eng Pagination: 214-21 Citation Subset: IM |
Affiliation:
|
Laboratory of Animal Nutrition, Faculty of Veterinary Medicine, Ghent University, Heidestraat 19, B-9820 Merelbeke, Belgium. adronie.verbrugghe@ugent.be |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animal Feed
/
analysis Animal Nutritional Physiological Phenomena Animals Blood Glucose / metabolism* Cats / blood, metabolism* Cross-Over Studies Diet / veterinary* Dietary Carbohydrates / administration & dosage Dietary Fats / administration & dosage Dietary Proteins / administration & dosage Energy Intake* Energy Metabolism / physiology* Female Insulin / blood* Male Random Allocation |
| Chemical | |
Reg. No./Substance:
|
0/Blood Glucose; 0/Dietary Carbohydrates; 0/Dietary Fats; 0/Dietary Proteins; 11061-68-0/Insulin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Maternal early pregnancy vitamin D status in relation to fetal and neonatal growth: results of the m...
Next Document: Oral administration of Lactobacillus acidophilus induces IL-12 production in spleen cell culture of ...