| The gestational timing of pregnancy loss: adaptive strategy? | |
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MedLine Citation:
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PMID: 19408286 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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This commentary links early pregnancy milestones (rescue of the corpus luteum, the luteal-placental shift, and blocking of the spiral arteries) with the pattern of gestation-specific pregnancy loss in humans. The objective is to describe the pattern and present an adaptive hypothesis: that high first trimester pregnancy loss results from selection to reduce the risk of maternal morbidity and mortality associated with human delivery. Specific questions within the broad framework of this hypothesis can be addressed with research in comparative physiology and endocrinology. |
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Authors:
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Donna Day Baird |
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Publication Detail:
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Type: Lectures; Research Support, N.I.H., Intramural |
Journal Detail:
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Title: American journal of human biology : the official journal of the Human Biology Council Volume: 21 ISSN: 1520-6300 ISO Abbreviation: Am. J. Hum. Biol. Publication Date: 2009 Nov-Dec |
Date Detail:
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Created Date: 2009-10-19 Completed Date: 2010-02-01 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8915029 Medline TA: Am J Hum Biol Country: United States |
Other Details:
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Languages: eng Pagination: 725-7 Citation Subset: IM |
Affiliation:
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Epidemiology Branch, National Institute of Environmental Health Sciences Research, Triangle Park, North Carolina 27709, USA. baird@niehs.nih.gov |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Abortion, Spontaneous* Adaptation, Physiological* Chorionic Gonadotropin / genetics Embryo Implantation / physiology Female Humans Pregnancy Pregnancy Maintenance / genetics, physiology* Selection, Genetic |
| Chemical | |
Reg. No./Substance:
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0/Chorionic Gonadotropin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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