| A genotype and phenotype database of genetically modified malaria-parasites. | |
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MedLine Citation:
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PMID: 20663715 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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The RMgm database, www.pberghei.eu, is a web-based, manually curated, repository containing information on genetically modified rodent-malaria parasites. It provides easy and rapid access to information on the genotype and phenotype of mutant and reporter parasites. The database also contains information on unpublished mutants without a clear phenotype and negative trials to disrupt genes. Information can be searched using pre-defined key features, such as phenotype, life-cycle stage, gene model, gene-tags and mutations. The information relating to the mutants is reciprocally linked to PlasmoDB and GeneDB. Access to mutant-parasite information, and gene function/ontology inferred from mutant phenotypes provides a timely resource aimed at enhancing research into Plasmodium gene function and (systems) biology. |
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Authors:
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Chris J Janse; Hans Kroeze; Auke van Wigcheren; Senad Mededovic; Jannik Fonager; Blandine Franke-Fayard; Andrew P Waters; Shahid M Khan |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2010-07-19 |
Journal Detail:
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Title: Trends in parasitology Volume: 27 ISSN: 1471-5007 ISO Abbreviation: Trends Parasitol. Publication Date: 2011 Jan |
Date Detail:
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Created Date: 2011-01-03 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100966034 Medline TA: Trends Parasitol Country: England |
Other Details:
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Languages: eng Pagination: 31-9 Citation Subset: IM |
Copyright Information:
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Copyright © 2010 Elsevier Ltd. All rights reserved. |
Affiliation:
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Leiden Malaria Research Group, Parasitology, Leiden University Medical Centre (LUMC), Albinusdreef 2, 2333 ZA, Leiden, The Netherlands. c.j.janse@lumc.nl |
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Comment In:
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Trends Parasitol. 2011 Jan;27(1):1-2
[PMID:
20667784
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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