| The genetics of gestational trophoblastic disease: a rare complication of pregnancy. | |
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MedLine Citation:
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PMID: 22469506 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Gestational choriocarcinoma is usually a rapidly spreading fatal disease, but it is curable if diagnosed early and treated. It is a unique malignancy that is a partial or complete allograft with a genotype that is not the same as the host genotype. It is most often preceded by an abnormal molar pregnancy. The surprising and unique androgenetic origin of complete hydatidiform molar pregnancies was first revealed by Kajii and Ohama in 1977. We describe the current understanding of the morphology, epidemiology and genetics of gestational trophoblastic disease that followed the milestone findings by Kajii and Ohama. |
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Authors:
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Lori Hoffner; Urvashi Surti |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Cancer genetics Volume: 205 ISSN: 2210-7762 ISO Abbreviation: Cancer Genet Publication Date: 2012 Mar |
Date Detail:
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Created Date: 2012-04-03 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101539150 Medline TA: Cancer Genet Country: United States |
Other Details:
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Languages: eng Pagination: 63-77 Citation Subset: IM |
Copyright Information:
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Copyright © 2012 Elsevier Inc. All rights reserved. |
Affiliation:
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Magee-Womens Research Institute and Foundation, Pittsburgh, PA, USA. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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