Document Detail


The genetic code--40 years on.
MedLine Citation:
PMID:  17369878     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The genetic code discovered 40 years ago, consists of 64 triplets (codons) of nucleotides. The genetic code is almost universal. The same codons are assigned to the same amino acids and to the same START and STOP signals in the vast majority of genes in animals, plants, and microorganisms. Each codon encodes for one of the 20 amino acids used in the synthesis of proteins. That produces some redundancy in the code and most of the amino acids being encoded by more than one codon. The two cases have been found where selenocysteine or pyrrolysine, that are not one of the standard 20 is inserted by a tRNA into the growing polypeptide.
Authors:
Maciej Szymański; Jan Barciszewski
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review     Date:  2007-03-20
Journal Detail:
Title:  Acta biochimica Polonica     Volume:  54     ISSN:  0001-527X     ISO Abbreviation:  Acta Biochim. Pol.     Publication Date:  2007  
Date Detail:
Created Date:  2007-03-27     Completed Date:  2007-10-15     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  14520300R     Medline TA:  Acta Biochim Pol     Country:  Poland    
Other Details:
Languages:  eng     Pagination:  51-4     Citation Subset:  IM    
Affiliation:
Institute of Bioorganic Chemistry of the Polish Academy of Sciences, Poznań, Poland.
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MeSH Terms
Descriptor/Qualifier:
Amino Acids / metabolism
Animals
Bacteria / genetics
Codon / genetics
DNA / chemistry,  genetics
Gene Expression Regulation
Genetic Code*
Humans
Plants / genetics
RNA, Transfer / genetics
Templates, Genetic
Transcription, Genetic
Chemical
Reg. No./Substance:
0/Amino Acids; 0/Codon; 9007-49-2/DNA; 9014-25-9/RNA, Transfer

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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