Document Detail


The genetic basis of tooth agenesis: Basic concepts and genes involved.
MedLine Citation:
PMID:  21911943     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Tooth agenesis is the most prevalent craniofacial congenital malformation in humans. While tooth agenesis may be associated with several syndromes, non-syndromic hypodontia refers to the congenital absence of a few teeth in the absence of any other deformity. Recent advances in molecular genetics have made it possible to identify the exact genes responsible for the development of teeth and trace the mutations that cause hypodontia. This paper reviews the literature regarding the genetic basis of non-syndromic tooth agenesis, methods used to study it, and the genes that have been definitively implicated in the agenesis of human dentition.
Authors:
Sharat Chandra Pani
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of the Indian Society of Pedodontics and Preventive Dentistry     Volume:  29     ISSN:  1998-3905     ISO Abbreviation:  J Indian Soc Pedod Prev Dent     Publication Date:    2011 Apr-Jun
Date Detail:
Created Date:  2011-09-13     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8710631     Medline TA:  J Indian Soc Pedod Prev Dent     Country:  India    
Other Details:
Languages:  eng     Pagination:  84-9     Citation Subset:  D    
Affiliation:
Department of Pediatric Dentistry, Riyadh Colleges of Dentistry and Pharmacy, Riyadh, Saudi Arabia.
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