Document Detail

A general class of preconditioners for statistical iterative reconstruction of emission computed tomography.
MedLine Citation:
PMID:  9050403     Owner:  NLM     Status:  MEDLINE    
A major drawback of statistical iterative image reconstruction for emission computed tomography is its high computational cost. The ill-posed nature of tomography leads to slow convergence for standard gradient-based iterative approaches such as the steepest descent or the conjugate gradient algorithm. In this paper new theory and methods for a class of preconditioners are developed for accelerating the convergence rate of iterative reconstruction. To demonstrate the potential of this class of preconditioners, a preconditioned conjugate gradient (PCG) iterative algorithm for weighted least squares reconstruction (WLS) was formulated for emission tomography. Using simulated positron emission tomography (PET) data of the Hoffman brain phantom, it was shown that the convergence rate of the PCG can reduce the number of iterations of the standard conjugate gradient algorithm by a factor of 2-8 times depending on the convergence criterion.
G Chinn; S C Huang
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  IEEE transactions on medical imaging     Volume:  16     ISSN:  0278-0062     ISO Abbreviation:  IEEE Trans Med Imaging     Publication Date:  1997 Feb 
Date Detail:
Created Date:  1997-03-24     Completed Date:  1997-03-24     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  8310780     Medline TA:  IEEE Trans Med Imaging     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1-10     Citation Subset:  IM    
Department of Molecular and Medical Pharmacology, UCLA School of Medicine 90095-6948, USA.
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MeSH Terms
Brain / radionuclide imaging
Computer Simulation
Deoxyglucose / analogs & derivatives,  diagnostic use
Fluorine Radioisotopes / diagnostic use
Fluorodeoxyglucose F18
Image Processing, Computer-Assisted* / statistics & numerical data
Least-Squares Analysis
Models, Statistical
Phantoms, Imaging
Radiopharmaceuticals / diagnostic use
Signal Processing, Computer-Assisted
Tomography, Emission-Computed* / statistics & numerical data
Grant Support
Reg. No./Substance:
0/Fluorine Radioisotopes; 0/Radiopharmaceuticals; 154-17-6/Deoxyglucose; 63503-12-8/Fluorodeoxyglucose F18

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