Document Detail

A gene controlling segregation of the Bacillus subtilis plasmid pC194.
MedLine Citation:
PMID:  3925293     Owner:  NLM     Status:  MEDLINE    
Plasmid pC194-1, a mutant of pC194, and chimeric derivatives of pC194-1 are segregationally unstable in B. subtilis. Such instability could be enhanced by exposure of pC194-1-carrying cells to methyl methanesulfonate. pC194-1 is distinct from pC194 in the addition of two A:T base pairs within the previously defined D region of pC194. Complementation experiments between pC194-1 and other plasmids suggest that the mutation of pC194-1 interferes with the production of a diffusible gene product required for plasmid maintenance.
J C Alonso; T A Trautner
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Molecular & general genetics : MGG     Volume:  198     ISSN:  0026-8925     ISO Abbreviation:  Mol. Gen. Genet.     Publication Date:  1985  
Date Detail:
Created Date:  1985-08-22     Completed Date:  1985-08-22     Revised Date:  2006-05-01    
Medline Journal Info:
Nlm Unique ID:  0125036     Medline TA:  Mol Gen Genet     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  427-31     Citation Subset:  IM    
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MeSH Terms
Bacillus subtilis / genetics*
Genes, Bacterial*
Genetic Complementation Test
Methyl Methanesulfonate / pharmacology
Plasmids* / drug effects,  radiation effects
Recombination, Genetic
Transformation, Bacterial
Ultraviolet Rays
Reg. No./Substance:
66-27-3/Methyl Methanesulfonate

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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