Document Detail


A gender perspective on short- and long term mortality in ST-elevation myocardial infarction - A report from the SWEDEHEART register.
MedLine Citation:
PMID:  23168004     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
BACKGROUND: Previous studies of patients admitted for ST-elevation myocardial infarction [STEMI] have indicated that women have a higher risk of early mortality than do men. These studies have presented limited information on gender related differences in the short term and almost no information on the long term. METHODS AND RESULTS: We analysed a prospective, consecutively included STEMI population consisting of 54,146 patients (35% women). This population consists of almost all patients hospitalised in Sweden between January 1, 1995 and December 31, 2006 as recorded in the SWEDEHEART register (formerly RIKS-HIA). Follow-up time ranged from one to 13years (mean 4.6). Women had a lower probability of being given reperfusion therapy, odds ratio [OR] 0.83 (95% confidence interval [CI] 0.79-0.88). During the time these STEMI patients were in the hospital, 13% of the women and 7% of men died, multivariable adjusted OR 1.21 (95% CI 1.11-1.32). During the follow up period, 46% of the women died as compared with 32% of the men. There was, however, no gender difference in age-adjusted risk of long term mortality (hazard ratio [HR] 0.98, 95% CI 0.95-1.01) whereas the multivariable adjusted risk was lower in women (HR 0.92, 95% CI 0.89-0.96). The long term risk of re-infarction was the same in men and women (HR 0.98, 95% CI 0.93-1.03) whereas men in the youngest group had a higher risk than women in that age group (HR 0.82, 95% CI 0.72-0.94). CONCLUSION: In STEMI, women had a higher risk of in-hospital mortality but the long-term risk of death was higher in men. More studies are needed in the primary percutaneous coronary intervention (pPCI) era that are designed to determine why women fare worse than men after STEMI during the first phase when they are in hospital.
Authors:
Sofia Sederholm Lawesson; Joakim Alfredsson; Mats Fredrikson; Eva Swahn
Related Documents :
23904954 - Effect of alcohol consumption on risk of hyperhomocysteinemia based on alcohol-related ...
25056464 - Assessment of sub-endometrial blood flow parameters following dydrogesterone and micron...
22930994 - "say it...near the flower shop": further evidence of the effect of flowers on mating.
23390894 - The clinical availability of non alcoholic fatty liver disease as an early predictor of...
15041084 - A single administration of testosterone improves visuospatial ability in young women.
18216474 - Medical history, drug exposure and the risk of psoriasis. evidence from an italian case...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-11-17
Journal Detail:
Title:  International journal of cardiology     Volume:  -     ISSN:  1874-1754     ISO Abbreviation:  Int. J. Cardiol.     Publication Date:  2012 Nov 
Date Detail:
Created Date:  2012-11-21     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8200291     Medline TA:  Int J Cardiol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.
Affiliation:
Department of Medical and Health Sciences, Division of Cardiovascular Medicine Linköping University Hospital, SE-581 85 Linköping, Sweden.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Defensive active coping facilitates chronic hyperglycaemia and endothelial dysfunction in African me...
Next Document:  Population trends and inequalities in incidence and short-term outcome of acute myocardial infarctio...