Document Detail

The gastro-duodenal epithelium in peptic ulceration.
MedLine Citation:
PMID:  4032128     Owner:  NLM     Status:  MEDLINE    
Mucosa-related bacteria, intra-epithelial lymphocytes and intra-epithelial polymorphonuclear leucocytes have been studied in 35 patients with duodenal ulceration, 27 patients with gastric ulceration and eight control subjects with normal gastro-duodenal mucosa. Mucosa-related bacteria were found in approximately 80 per cent of peptic ulcer patients and rarely in controls. The bacteria were most numerous at the sites of active chronic gastritis. There was a positive correlation between the number of bacteria and the number of intra-epithelial polymorphonuclear leucocytes. There was no correlation between the peripheral blood white cell count and the number of intra-epithelial polymorphonuclear leucocytes. The number of intra-epithelial lymphocytes was increased in peptic ulceration.
H W Steer
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of pathology     Volume:  146     ISSN:  0022-3417     ISO Abbreviation:  J. Pathol.     Publication Date:  1985 Aug 
Date Detail:
Created Date:  1985-10-09     Completed Date:  1985-10-09     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0204634     Medline TA:  J Pathol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  355-62     Citation Subset:  IM    
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MeSH Terms
Bacteria / isolation & purification
Duodenal Ulcer / microbiology,  pathology*
Duodenum / ultrastructure
Epithelium / ultrastructure
Gastric Mucosa / microbiology,  ultrastructure*
Intestinal Mucosa / ultrastructure*
Microscopy, Electron
Stomach Ulcer / microbiology,  pathology*

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