| Is gamma-band activity in the local field potential of V1 cortex a "clock" or filtered noise? | |
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MedLine Citation:
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PMID: 21715631 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Gamma-band (25-90 Hz) peaks in local field potential (LFP) power spectra are present throughout the cerebral cortex and have been related to perception, attention, memory, and disorders (e.g., schizophrenia and autism). It has been theorized that gamma oscillations provide a "clock" for precise temporal encoding and "binding" of signals about stimulus features across brain regions. For gamma to function as a clock, it must be autocoherent: phase and frequency conserved over a period of time. We computed phase and frequency trajectories of gamma-band bursts, using time-frequency analysis of LFPs recorded in macaque primary visual cortex (V1) during visual stimulation. The data were compared with simulations of random networks and clock signals in noise. Gamma-band bursts in LFP data were statistically indistinguishable from those found in filtered broadband noise. Therefore, V1 LFP data did not contain clock-like gamma-band signals. We consider possible functions for stochastic gamma-band activity, such as a synchronizing pulse signal. |
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Authors:
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Samuel P Burns; Dajun Xing; Robert M Shapley |
Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S. |
Journal Detail:
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Title: The Journal of neuroscience : the official journal of the Society for Neuroscience Volume: 31 ISSN: 1529-2401 ISO Abbreviation: J. Neurosci. Publication Date: 2011 Jun |
Date Detail:
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Created Date: 2011-06-30 Completed Date: 2011-09-13 Revised Date: 2011-09-22 |
Medline Journal Info:
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Nlm Unique ID: 8102140 Medline TA: J Neurosci Country: United States |
Other Details:
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Languages: eng Pagination: 9658-64 Citation Subset: IM |
Affiliation:
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Center for Neural Science and Courant Institute of Mathematical Sciences, New York University, New York 10012, USA. sburns9@jhu.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Attention
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physiology Biological Clocks / physiology* Brain Waves / physiology* Electrophysiology Evoked Potentials, Visual Humans Models, Neurological Neurons / physiology Photic Stimulation Visual Cortex / physiology* Visual Perception / physiology* |
| Grant Support | |
ID/Acronym/Agency:
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R01 EY-01472/EY/NEI NIH HHS; T32 EY007158-07/EY/NEI NIH HHS; T32-EY007158/EY/NEI NIH HHS |
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