| Is galectin-3 antibody a useful marker in the diagnosis of malignant pleural mesothelioma? | |
MedLine Citation:
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PMID: 23537297 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Malignant pleural mesothelioma (MPM) is a challenging diagnosis characterized by the absence of real specific diagnostic markers. Positivity with the galectin-3 antibody was assessed by a cytoplasmic expression in 17 MPM. Fourteen cases expressed the galectin-3 antibody. The three negative cases consisted of epithelioid, biphasic, and sarcomatoid MPM. The 14 positive cases consisted of epithelioid MPM in 12 cases, sarcomatoid MPM in one case, and biphasic MPM in one case. In spite of our inability to prove the real diagnostic value of the galectin-3 antibody, our findings make us wonder about the implication of this antibody in the carcinogenesis of MPM. |
Authors:
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Mona Mlika; Aida Ayadi-Kaddour; Meriem Ksantini; Saadia Bouraoui; Sabah Mzabi; Faouzi El Mezni |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of immunoassay & immunochemistry Volume: 34 ISSN: 1532-4230 ISO Abbreviation: J Immunoassay Immunochem Publication Date: 2013 Apr |
Date Detail:
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Created Date: 2013-03-29 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100963688 Medline TA: J Immunoassay Immunochem Country: England |
Other Details:
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Languages: eng Pagination: 111-25 Citation Subset: IM |
Affiliation:
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a Department of Pathology , Abderrahman Mami Hospital , Ariana , Tunis , Tunisia. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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