Document Detail

The future of pharmacoeconomics: bridging science and practice.
MedLine Citation:
PMID:  8930435     Owner:  NLM     Status:  MEDLINE    
In the context of new challenges, issues facing the science, practice, and future of pharmacoeconomics will be discussed. Certain methodologic weaknesses have been observed in published pharmacoeconomic studies, and compromises need to be made between developing an "ideal" method and allowing a study to remain practicable. The objective is to reach a balance between clinical trial-based studies and projective models; trials have high internal validity but low external validity, while models can help explore relevance to real-life settings. Cross-national differences also have an important impact on pharmacoeconomic data; however, using some basic standardized guidelines results from pharmacoeconomic studies may be generalized to other settings. The use of pharmacoeconomic results by decision makers in the United Kingdom has been restrained by unclear priorities within their authority and by the limited availability of credible studies. The future of pharmacoeconomics lies in developing both trial-based and modeling studies, improving their credibility, and meeting the needs of decision makers.
M F Drummond
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical therapeutics     Volume:  18     ISSN:  0149-2918     ISO Abbreviation:  Clin Ther     Publication Date:    1996 Sep-Oct
Date Detail:
Created Date:  1997-02-12     Completed Date:  1997-02-12     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  7706726     Medline TA:  Clin Ther     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  969-78; discussion 968     Citation Subset:  IM    
Centre for Health Economics, University of York, Haslington, United Kingdom.
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MeSH Terms
Clinical Trials as Topic
Economics, Pharmaceutical / trends*
United States

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