Document Detail


The future of heavy ion radiotherapy.
MedLine Citation:
PMID:  19175122     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Currently, there is an increasing interest in heavy ion radiotherapy (RT) and a number of new facilities are being installed in Europe and Japan. This development is accompanied by intensive technical, physical, and clinical research. The authors identify six research fields where progress is likely and propose a thesis on the expected achievements for each of the fields: (1) Synchrotrons with active energy variation and three-dimensional beam scanning will be the standard in ion beam RT. (2) Common standards for precise measurement, prescription, and reporting of dose will be available. (3) Intensity-modulated particle therapy will be state-of-the-art. (4) Time-adaptive treatments of moving targets will be feasible. (5) Therapeutic effectiveness of heavy ions will be known for the most important indications while cost effectiveness will remain to be shown. (6) The potential of high-linear energy transfer radiation will be known. The rationale for each of these theses is described.
Authors:
Oliver Jäkel; Christian P Karger; Jürgen Debus
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Medical physics     Volume:  35     ISSN:  0094-2405     ISO Abbreviation:  Med Phys     Publication Date:  2008 Dec 
Date Detail:
Created Date:  2009-01-29     Completed Date:  2009-02-20     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0425746     Medline TA:  Med Phys     Country:  United States    
Other Details:
Languages:  eng     Pagination:  5653-63     Citation Subset:  IM    
Affiliation:
Department of Medical Physics in Radiation Oncology, German Cancer Research Center, Heidelberg, Germany. o.jaekel@dkfz.de
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MeSH Terms
Descriptor/Qualifier:
Clinical Trials as Topic
Equipment Design
Heavy Ions / therapeutic use*
Humans
Radiation Oncology / methods,  trends
Radiometry / methods
Radiotherapy / instrumentation*,  methods*,  trends
Radiotherapy Planning, Computer-Assisted / methods
Relative Biological Effectiveness
Synchrotrons
Time Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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