Document Detail

A further contribution to the choice of the dose for L-tryptophan load test.
MedLine Citation:
PMID:  583197     Owner:  NLM     Status:  MEDLINE    
The analysis of the results of a study on the urinary excretion of metabolites "via kynurenine" after the ingestion in man of different amounts of tryptophan is reported. Of the three doses of L-tryptophan administered to the subjects, that is 2 g pro capite, 50 mg/Kg and 75 mg/Kg body weight, it is preferable to choose that of 50 mg/Kg b.w. as a load test. Such a dose assures an excretion of the more important metabolites without significant variations between men and women and without producing overloading effects.
G Allegri; C Costa; A De Antoni
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta vitaminologica et enzymologica     Volume:  32     ISSN:  0300-8924     ISO Abbreviation:  Acta Vitaminol. Enzymol.     Publication Date:  1978  
Date Detail:
Created Date:  1980-02-15     Completed Date:  1980-02-15     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0135063     Medline TA:  Acta Vitaminol Enzymol     Country:  ITALY    
Other Details:
Languages:  eng     Pagination:  163-6     Citation Subset:  IM    
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MeSH Terms
Aminohippuric Acids / urine
Anthranilic Acids / urine
Body Weight
Kynurenic Acid / urine
Kynurenine / metabolism*,  urine
Sex Factors
Tryptophan / administration & dosage*,  metabolism
Xanthurenates / urine
Reg. No./Substance:
0/Aminohippuric Acids; 0/Anthranilic Acids; 0/Xanthurenates; 343-65-7/Kynurenine; 492-27-3/Kynurenic Acid; 73-22-3/Tryptophan

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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