Document Detail

The function of arachnoid villi/granulations revisited.
MedLine Citation:
PMID:  8997824     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To establish the current viewpoint with regards to the role of arachnoid villi/granulations in cerebrospinal fluid (CSF) absorption. DESIGN: Retrospective study. SUBJECTS: Journal articles published between 1913 and 1993. MAIN OUTCOME MEASURE: The contribution of arachnoid villi/granulations to CSF absorption from the subarachnoid space. RESULTS: From available literature, it is yet to be proved that arachnoid villi/granulations are the major sites for CSF absorption from the subarachnoid space into the venous system. They may, however, play an important role in the absorption of CSF's waste products of neuronal metabolism (mainly CSF proteins) under normal physiological conditions. Furthermore, it would appear that, under pathological conditions, the absorption of CSF proteins can take place at other CSF absorption sites. CONCLUSION: The paucity of data on the relationship between the development of arachnoid villi, the superior sagittal sinus, the superficial cortical vessels and the subarachnoid space warrants that an ontogenic study be conducted in order to achieve a better understanding of the function of arachnoid villi which is currently speculative.
G Mawera; S A Asala
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  The Central African journal of medicine     Volume:  42     ISSN:  0008-9176     ISO Abbreviation:  Cent Afr J Med     Publication Date:  1996 Sep 
Date Detail:
Created Date:  1997-02-11     Completed Date:  1997-02-11     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  0372566     Medline TA:  Cent Afr J Med     Country:  ZIMBABWE    
Other Details:
Languages:  eng     Pagination:  281-4     Citation Subset:  IM    
Department of Anatomy, Faculty of Medicine, University of Zimbabwe, Harare, Zimbabwe.
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MeSH Terms
Arachnoid / anatomy & histology,  physiology*
Cerebrospinal Fluid / physiology*
Cerebrospinal Fluid Proteins / metabolism
Retrospective Studies
Reg. No./Substance:
0/Cerebrospinal Fluid Proteins

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