Document Detail


The function of the Estrogen Receptor in skeletal muscle mass and regeneration.
MedLine Citation:
PMID:  24995827     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
In the manuscript "Oestrogen-dependent satellite cell activation and proliferation following a running exercise occurs via the PI3K signalling pathway and not IGF-1." by Mangan et al. sheds new light on the molecular mechanisms involved in the effects of exercise training and estradiol treatment on the activation of satellite cells. The authors focus particularly on the interaction between IGF-1 and estradiol and the role of the PI3K signaling pathway in mediating the effects of estradiol on satellite cell activation. With this work the authors make a significant contribution to understanding the mechanisms mediating the effects of male and female sex hormones on skeletal muscle satellite cell regulation. This article is protected by copyright. All rights reserved.
Authors:
Patrick Diel
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Publication Detail:
Type:  EDITORIAL     Date:  2014-7-4
Journal Detail:
Title:  Acta physiologica (Oxford, England)     Volume:  -     ISSN:  1748-1716     ISO Abbreviation:  Acta Physiol (Oxf)     Publication Date:  2014 Jul 
Date Detail:
Created Date:  2014-7-4     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101262545     Medline TA:  Acta Physiol (Oxf)     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
This article is protected by copyright. All rights reserved.
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