Document Detail

The frequency of venous thrombosis in cemented and non-cemented hip arthroplasty.
MedLine Citation:
PMID:  8666626     Owner:  NLM     Status:  MEDLINE    
We randomised 250 patients undergoing unilateral, elective hip arthroplasty for osteoarthritis to receive either a cemented or a non-cemented Mallory Head prosthesis. Aspirin was used as prophylaxis against thromboembolism during the first half of the study and adjusted-dose warfarin during the second half. Postoperatively, all patients were asked to have bilateral venography and 80% agreed. All were evaluated clinically for pulmonary embolism. There was no difference in the frequency of deep-venous thrombosis between the two groups (50% cemented nu 47% non-cemented, p = 0.73; 95% CI of the difference -13.6% to 19.3%). Three of the 64 patients (5%) in whom venography had demonstrated isolated distal thrombi developed pulmonary emboli.
A Laupacis; C Rorabeck; R Bourne; P Tugwell; R Bullas; R Rankin; A D Vellet; D Feeny; C Wong
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Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Journal of bone and joint surgery. British volume     Volume:  78     ISSN:  0301-620X     ISO Abbreviation:  J Bone Joint Surg Br     Publication Date:  1996 Mar 
Date Detail:
Created Date:  1996-08-08     Completed Date:  1996-08-08     Revised Date:  2010-11-10    
Medline Journal Info:
Nlm Unique ID:  0375355     Medline TA:  J Bone Joint Surg Br     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  210-2     Citation Subset:  AIM; IM    
Division of General Medicine, Department of Medicine, Ottawa General Hospital, Ontario, Canada.
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MeSH Terms
Anticoagulants / therapeutic use
Aspirin / therapeutic use
Hip Prosthesis* / methods
Middle Aged
Ontario / epidemiology
Pulmonary Embolism / diagnosis
Thrombophlebitis / epidemiology*,  prevention & control,  radiography
Reg. No./Substance:
0/Anticoagulants; 50-78-2/Aspirin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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