Document Detail


The frequency of fetal bradycardia during selective epidural anaesthesia.
MedLine Citation:
PMID:  1199705     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The frequency of marked fetal bradycardia (FB) during selective lumbar epidural anaesthesia with 0.25% or 0.5% bupivacaine (Marcain, Bofors) without adrenaline in doses of 5 ml to 8 ml is reported. 35 patients were monitored by means of the Hewlett-Packard Cardiotocograph with Hon's spiral scalp electrode and a transcervical catheter connected to a Hewlett-Packard (1280 B/C) physiological pressure transducer. Only patients with a normal cardiotocogram (CTG) before anaesthesia are included. During the second stage pathological fetal heart rate (FHR) patterns and technical artefacts are common, therefore the CTGs recorded in this period were not considered. In the 35 patients the total time of intrauterine monitoring was 119 hours. During this period 125 doses of 0.25% and 23 doses of 0.5% bupivacaine were given. In 33 parturients the FHR changes observed were insignificant. In one case a period of marked FB was seen. One parturient developed acute hypotension with a synchronous FB while lying in the supine position. It is concluded that continuous lumbar epidural anaesthesia with bupivacaine without adrenaline does not precipitate FB during the first stage when care is taken to avoid maternal hypotension.
Authors:
J M Maltau
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta obstetricia et gynecologica Scandinavica     Volume:  54     ISSN:  0001-6349     ISO Abbreviation:  Acta Obstet Gynecol Scand     Publication Date:  1975  
Date Detail:
Created Date:  1976-02-27     Completed Date:  1976-02-27     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370343     Medline TA:  Acta Obstet Gynecol Scand     Country:  SWEDEN    
Other Details:
Languages:  eng     Pagination:  357-61     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Anesthesia, Epidural / adverse effects*
Anesthesia, Obstetrical / adverse effects*
Blood Pressure / drug effects
Bupivacaine / adverse effects*
Depression, Chemical
Female
Fetal Heart / drug effects*
Heart Rate / drug effects*
Humans
Maternal-Fetal Exchange / drug effects
Pregnancy
Pressure
Chemical
Reg. No./Substance:
2180-92-9/Bupivacaine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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