| The frequency of ectopic thymic tissue in the necks of patients without any thymic disease. | |
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MedLine Citation:
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PMID: 17534235 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Incidences of ectopic thymic tissue in the neck have been reported in various conditions. Despite their diversity, there are only a few studies focusing on patients without any thymic disease. The goal of this study was to detect the frequency of ectopic thymic tissue in the necks of adult patients without any thymic disease. MATERIAL/METHODS: Ninety patients with thyroid disorder who were candidate for thyroidectomy were selected. Five specimens were taken from each patient, including two biopsies before thyroidectomy from the right and left thyrothymic ligament just near the thyroid. The other specimens were taken after thyroidectomy: two from right and left carotid sheet at the base of the neck and the fifth from the adipose tissue just above the fourth tracheal cartilage. The specimens were stained with H&E and cytokeratin antibody to detect thymic tissue. RESULTS: Ectopic thymic tissue was found in four cases (4.45%), one by H&E and the others by immunohistochemical staining. CONCLUSIONS: In patients with myasthenia gravis, hyperplasia of thymic tissue occurs in their thymus gland and ectopic thymic tissue as well. As a result, the probability of finding ectopic thymic tissue in such a patient is higher than in patients without any thymic disease. Also, removing of this tissue can improve the outcome of patients. |
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Authors:
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Seid Abbas Tabatabaie; Seid Mozafar Hashemi; Behnam Sanei; Mohammad Hossein Sanei |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Medical science monitor : international medical journal of experimental and clinical research Volume: 13 ISSN: 1234-1010 ISO Abbreviation: Med. Sci. Monit. Publication Date: 2007 Jun |
Date Detail:
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Created Date: 2007-05-30 Completed Date: 2007-08-17 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9609063 Medline TA: Med Sci Monit Country: Poland |
Other Details:
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Languages: eng Pagination: CR283-85 Citation Subset: IM |
Affiliation:
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Department of Thoracic Surgery, Isfahan University of Medical Sciences, School of Medicine, Iran. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Biopsy Choristoma / diagnosis, epidemiology, pathology* Female Humans Iran / epidemiology Male Middle Aged Neck / pathology* Thymus Gland / pathology* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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