Document Detail

Is the free androgen index a useful clinical marker in male patients?
MedLine Citation:
PMID:  9871405     Owner:  NLM     Status:  MEDLINE    
The clinical relevance of the free androgen index (FAI), a ratio of total testosterone (T) to sex-hormone binding globulin (SHBG), was investigated in a regional population of men (n = 40) and women (n = 30). The FAI correlated well with free testosterone (T) in both men (r = 0.551, p < 0.001) and women (r = 0.454, p < 0.01). However, there was considerable variability among individual patients. Moreover, the FAI showed no association with sperm parameters in male patients, although total T and free T showed weak associations. The FAI may be a cost-effective alternative to free T measurement in the diagnosis of oligomenorrhea and hirsutism in women as previously shown, but may have little relevance in men.
J D Brannian; P Long; D O Kreger
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  South Dakota journal of medicine     Volume:  51     ISSN:  -     ISO Abbreviation:  S D J Med     Publication Date:  1998 Dec 
Date Detail:
Created Date:  1999-01-20     Completed Date:  1999-01-20     Revised Date:  2014-05-19    
Medline Journal Info:
Nlm Unique ID:  0040162     Medline TA:  S D J Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  449-51     Citation Subset:  IM    
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MeSH Terms
Hirsutism / blood,  diagnosis*
Infertility, Male / blood,  diagnosis*
Luminescent Measurements
Oligomenorrhea / blood,  diagnosis*
Oligospermia / blood,  diagnosis
Polycystic Ovary Syndrome / blood,  diagnosis*
Retrospective Studies
Sex Factors
Sex Hormone-Binding Globulin / analysis*
Sperm Count
Testosterone / blood*
Reg. No./Substance:
0/Sex Hormone-Binding Globulin; 3XMK78S47O/Testosterone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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