Document Detail


The fragile-X syndrome: a growing gene causing familial intellectual disability.
MedLine Citation:
PMID:  8173220     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The fragile-X syndrome is the most common cause of familial intellectual disability. Recently, the gene related to the fragile-X syndrome [the 'fragile-X mental retardation'-1 (FMR-1) gene] has been isolated. In this review, clinical and molecular aspects of the fragile-X syndrome, current benefits and future prospects are discussed.
Authors:
L B De Vries; D J Halley; B A Oostra; M F Niermeijer
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Journal of intellectual disability research : JIDR     Volume:  38 ( Pt 1)     ISSN:  0964-2633     ISO Abbreviation:  J Intellect Disabil Res     Publication Date:  1994 Feb 
Date Detail:
Created Date:  1994-06-09     Completed Date:  1994-06-09     Revised Date:  2009-11-19    
Medline Journal Info:
Nlm Unique ID:  9206090     Medline TA:  J Intellect Disabil Res     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  1-8     Citation Subset:  IM    
Affiliation:
Department of Clinical Genetics, Erasmus University, Rotterdam, The Netherlands.
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MeSH Terms
Descriptor/Qualifier:
Female
Fragile X Syndrome / diagnosis,  genetics*,  psychology
Genetic Testing
Heterozygote Detection
Humans
Intelligence / genetics
Male
Mental Retardation / diagnosis,  genetics*,  psychology
Pedigree
Phenotype

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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