Document Detail

A four-year prospective study on microbial ecology of explanted prosthetic hips in 52 patients with "aseptic" prosthetic joint loosening.
MedLine Citation:
PMID:  8801090     Owner:  NLM     Status:  MEDLINE    
The bacteriology of explanted prosthetic hips and surrounding soft tissue was studied in 52 patients undergoing surgical revision for joint loosening. In a prospective four-year study, positive bacterial cultures were recorded in 34 (76%) patients. Coagulase-negative staphylococci were the predominant isolates, and 11 patients (33%) had more than three organisms isolated, 7 (20%) had two only, and 11 (33%) had one species. Among the 23 patients from whom specimens from all 11 predetermined anatomic sites were cultured, the highest frequency of positive cultures (52% and 47%) came from the shaft and capsular tissue, respectively. Organisms were less frequently recovered from the cement and acetabulum (13% and 4%, respectively). Using molecular typing in eight patients with paired isolates of the same species, clonal identity was found in four. An additional patient underwent a second revision for loosening 17 months after the first revision and the same clone of Staphylococcus epidermidis was isolated on both occasions.
F Perdreau-Remington; D Stefanik; G Peters; C Ludwig; J Rütt; R Wenzel; G Pulverer
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology     Volume:  15     ISSN:  0934-9723     ISO Abbreviation:  Eur. J. Clin. Microbiol. Infect. Dis.     Publication Date:  1996 Feb 
Date Detail:
Created Date:  1996-10-01     Completed Date:  1996-10-01     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8804297     Medline TA:  Eur J Clin Microbiol Infect Dis     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  160-5     Citation Subset:  IM    
Institute of Medical Microbiology and Hygiene, University of Cologne, Germany.
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MeSH Terms
Aged, 80 and over
Colony Count, Microbial
Corynebacterium / growth & development,  isolation & purification
Electrophoresis, Gel, Pulsed-Field
Escherichia coli / growth & development,  isolation & purification
Gram-Positive Bacteria / growth & development,  isolation & purification*
Hip Prosthesis / microbiology*
Middle Aged
Prospective Studies
Prosthesis Failure
Staphylococcus / growth & development,  isolation & purification

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