| The forms of variability in a cell population as well as in an organism population. The biology of the development of the cardiac myocytes | |
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MedLine Citation:
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PMID: 7991235 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Variability of cells is analyzed using data obtained in studies on polyploidy in the heart muscle and on ontogenetic changes in the number of myocytes. In normal myocardium, variation in the number and ploidy of muscle cells is observed. The types of genomic variation are similar to those found in populations of organisms, i. e., to hereditary and modifying variation. In studies on modifications of the myocyte genome, heart growth reserves were revealed, which manifest themselves in pathological states associated with myocardial hypertrophy. These reserves depend on the level of myocardial polyploidy that is determined during early postnatal development. |
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Authors:
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V Ia Brodskiĭ |
Publication Detail:
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Type: English Abstract; Journal Article; Review |
Journal Detail:
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Title: Ontogenez Volume: 25 ISSN: 0475-1450 ISO Abbreviation: Ontogenez Publication Date: 1994 Sep-Oct |
Date Detail:
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Created Date: 1995-01-11 Completed Date: 1995-01-11 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 0341527 Medline TA: Ontogenez Country: RUSSIA |
Other Details:
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Languages: rus Pagination: 29-43 Citation Subset: IM |
Vernacular Title:
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Formy izmenchivosti v kletochnoĭ populiatsii takie zhe, kak v populiatsii organizmov. Biologiia razvitiia serdechnykh miotsitov. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Cardiomegaly / genetics, pathology Cytogenetics Genetic Variation* Genome Heart / growth & development* Humans Myocardium / cytology* Ploidies |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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