Document Detail

A fluorescein angiographic study on carbon disulfide retinopathy among workers in viscose rayon factories.
MedLine Citation:
PMID:  6654514     Owner:  NLM     Status:  MEDLINE    
In order to clarify the pathogenesis of carbon disulfide retinopathy, fluorescein fundus angiograms were analyzed for 143 workers exposed to CS2 and 40 unexposed workers (reference) from viscose rayon factories. Retinal abnormalities, characterized by saccular microaneurysms, ellipsoidal microaneurysms and loop formation of small vessels, and atrophic/degenerative changes of pigmentary epithelium, were found in workers exposed to CS2. Saccular microaneurysms were found in 45.5% of the CS2 workers and 7.5% of the reference workers (P less than 0.05). Ellipsoidal microaneurysms or loop formation were found in 14.0% of the CS2 workers and 5.0% of the reference workers. Atrophic/degenerative changes of the pigmentary epithelium were found in 32.9% of the CS2 workers and 15.0% of the reference workers (P less than 0.05). Significant correlations were found between the prevalence of these retinal abnormalities and the CS2 exposure index.
I Karai; K Sugimoto; S Goto
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  International archives of occupational and environmental health     Volume:  53     ISSN:  0340-0131     ISO Abbreviation:  Int Arch Occup Environ Health     Publication Date:  1983  
Date Detail:
Created Date:  1984-02-23     Completed Date:  1984-02-23     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7512134     Medline TA:  Int Arch Occup Environ Health     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  91-9     Citation Subset:  IM    
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MeSH Terms
Age Factors
Aneurysm / chemically induced*,  diagnosis
Carbon Disulfide / adverse effects*
Fluorescein Angiography
Middle Aged
Occupational Diseases / chemically induced*,  diagnosis
Pigment Epithelium of Eye / drug effects
Retinal Artery / drug effects*
Retinal Degeneration / chemically induced*,  diagnosis
Textile Industry*
Time Factors
Reg. No./Substance:
61788-77-0/rayon; 75-15-0/Carbon Disulfide; 9004-34-6/Cellulose

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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