Document Detail


A fixed dose combination of ibuprofen and famotidine.
MedLine Citation:
PMID:  19659445     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
The NSAID class of medications is frequently used for mild to moderate pain. While overall safe, NSAIDs have several important adverse effects including esophageal, gastric and duodenal ulceration which limit their use. This has led to the development of NSAIDs with either less gastrointestinal side effects or concurrent use of medications to prevent NSAID gastrointestinal side effects. While several classes of medications exist for the prevention of gastrointestinal side effects, few combination treatments are available in a single pill. Towards this end, a combination pill of ibuprofen and famotidine (HZT-501, Horizon Therapeutics, Skokie, IL. USA) has been developed.
Authors:
John W Birk; Matthew Myers
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Expert opinion on investigational drugs     Volume:  18     ISSN:  1744-7658     ISO Abbreviation:  Expert Opin Investig Drugs     Publication Date:  2009 Sep 
Date Detail:
Created Date:  2009-08-14     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9434197     Medline TA:  Expert Opin Investig Drugs     Country:  England    
Other Details:
Languages:  eng     Pagination:  1385-91     Citation Subset:  IM    
Affiliation:
Chief, Gastroenterology, Department of Medicine, University of Connecticut Health Center, 263 Farmington Avenue, MC-1845, Farmington, Connecticut, CT 06030, USA. birk@uchc.edu
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