Document Detail

The first successful paternity through in vitro fertilization-intracytoplasmic sperm injection with a man homozygous for the 5α-reductase-2 gene mutation.
MedLine Citation:
PMID:  21334614     Owner:  NLM     Status:  Publisher    
OBJECTIVE: To report a case of successful paternity from a male homozygous for 5α-reductase-2 deficiency. DESIGN: Case report. SETTING: Academic center, division of reproductive endocrinology. PATIENT(S): A 45-year-old Dominican man and his 32-year-old wife. INTERVENTION(S): In vitro fertilization and intracytoplasmic sperm injection. MAIN OUTCOME MEASURE(S): Pregnancy. RESULT(S): Viable twin gestation. CONCLUSION(S): Men homozygous for 5α-reductase-2 deficiency can achieve biologic paternity through in vitro fertilization with intracytoplasmic sperm injection despite severely abnormal semen parameters.
Hey-Joo Kang; Julianne Imperato-McGinley; Yuan-Shan Zhu; Li-Qun Cai; Peter Schlegel; Gianpiero Palermo; Zev Rosenwaks
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-2-18
Journal Detail:
Title:  Fertility and sterility     Volume:  -     ISSN:  1556-5653     ISO Abbreviation:  -     Publication Date:  2011 Feb 
Date Detail:
Created Date:  2011-2-21     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0372772     Medline TA:  Fertil Steril     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2011 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.
Ronald O. Perelman and Claudia Cohen Center for Reproductive Medicine, Weill Medical College of Cornell University, New York, New York.
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