Document Detail

The first infant to survive a generalized BCG infection.
MedLine Citation:
PMID:  6753467     Owner:  NLM     Status:  MEDLINE    
A 17-month-old boy who contracted a severe generalized BCG infection is reported. He was treated for 2 years with streptomycin, isoniazide and rifampicin and is now, at the age of 5 years, apparently cured. The boy had an unexplained discrepancy between humoral and cellular PPD reactivity for several years, but conventional immunological studies including plasma immunoglobulin levels, blast transformation as well as MLC reactivity were all normal. This is, to the best of our knowledge, the first child reported who has survived a generalized BCG infection.
G Källenius; E Möller; O Ringdén; B Strandvik; P Sundelin
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Acta paediatrica Scandinavica     Volume:  71     ISSN:  0001-656X     ISO Abbreviation:  Acta Paediatr Scand     Publication Date:  1982 Jan 
Date Detail:
Created Date:  1982-12-16     Completed Date:  1982-12-16     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0000211     Medline TA:  Acta Paediatr Scand     Country:  SWEDEN    
Other Details:
Languages:  eng     Pagination:  161-5     Citation Subset:  IM    
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MeSH Terms
Antibodies, Bacterial / analysis
B-Lymphocytes / immunology
Child, Preschool
Isoniazid / therapeutic use
Lymphocyte Activation
Mitogens / pharmacology
Mycobacterium bovis / immunology
Plaque Assay
Rifampin / therapeutic use
Streptomycin / therapeutic use
T-Lymphocytes / immunology
Tuberculosis / drug therapy*,  immunology
Reg. No./Substance:
0/Antibodies, Bacterial; 0/Mitogens; 13292-46-1/Rifampin; 54-85-3/Isoniazid; 57-92-1/Streptomycin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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