| The fine structure of thymoma, with emphasis on its differential diagnosis. A study of ten cases. | |
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MedLine Citation:
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PMID: 1080957 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In this study, thymoma is defined as a neoplasm of the epithelial-reticular framework cells of the thymus. As in the normal thymus, these cells regularly displayed branching tonofilaments, macuale adherens, elongated processes, and basal lamina. These characteristics proved useful in the differential diagnosis of thymoma from a variety of anterior mediastinal tumors including thymic carcinoid, lymphoma, germinoma (seminoma type), and fibrous mesothelioma. Lymphocytes in the thymomas often showed mitotic activity and a moderate degree of transformation. The significance of this and the gland-like spaces, vacuolated epithelial cells, starry-sky appearance, emperipolesis, and perivascular spaces is discussed. |
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Authors:
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G D Levine; J Rosai; R M Bearman; A Polliack |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The American journal of pathology Volume: 81 ISSN: 0002-9440 ISO Abbreviation: Am. J. Pathol. Publication Date: 1975 Oct |
Date Detail:
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Created Date: 1975-12-29 Completed Date: 1975-12-29 Revised Date: 2009-11-18 |
Medline Journal Info:
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Nlm Unique ID: 0370502 Medline TA: Am J Pathol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 49-86 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Carcinoid Tumor / diagnosis Desmosomes / ultrastructure Diagnosis, Differential Dysgerminoma / diagnosis Epithelial Cells Epithelium / ultrastructure Female Hodgkin Disease / diagnosis Humans Lymphocyte Activation Lymphoma / diagnosis Male Middle Aged T-Lymphocytes / ultrastructure Thymoma / diagnosis, pathology* Thymus Gland / pathology Thymus Neoplasms / diagnosis, pathology* Vacuoles |
| Comments/Corrections | |
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