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The fine structural organisation of Rous tumour cells.
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MedLine Citation:
PMID:  13481019     Owner:  NLM     Status:  MEDLINE    
The fibroblast-like tumour cells of Rous sarcomata have been studied in thin sections with the electron microscope. A description is given of the fine structure of the cells which includes some features not hitherto recorded. The tightly packed piles of smooth cisternae usually found only in the centrosome region have been observed, in individual Rous cells, in two separate areas of cytoplasm at opposite poles of the nucleus. Continuity between the perinuclear space and the lumen of rough surfaced cisternae of the endoplasmic reticulum has frequently been found; a similar continuity between the cisternae and the exterior of the cell has also been seen. In some cases, the cell membrane has been shown to have an unbroken connection with the outer nuclear membrane through continuity with the limiting membranes of elements of the endoplasmic reticulum. These findings are discussed.
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of biophysical and biochemical cytology     Volume:  3     ISSN:  0095-9901     ISO Abbreviation:  J Biophys Biochem Cytol     Publication Date:  1957 Nov 
Date Detail:
Created Date:  1958-12-01     Completed Date:  2000-07-01     Revised Date:  2010-06-22    
Medline Journal Info:
Nlm Unique ID:  17840020R     Medline TA:  J Biophys Biochem Cytol     Country:  Not Available    
Other Details:
Languages:  eng     Pagination:  851-8     Citation Subset:  OM    
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MeSH Terms
Microscopy, Electron*
Neoplasms / pathology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Full Text
Journal Information
Journal ID (nlm-ta): J Biophys Biochem Cytol
ISSN: 0095-9901
Publisher: The Rockefeller University Press
Article Information
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Copyright © Copyright, 1957, by The Rockefeller Institute for Medical Research
Received Day: 8 Month: 7 Year: 1957
Print publication date: Day: 25 Month: 11 Year: 1957
Volume: 3 Issue: 6
First Page: 851 Last Page: 858
ID: 2224136
PubMed Id: 13481019

M. A. Epstein
From The Bland-Sutton Institute of Pathology, The Middlesex Hospital, London

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