Document Detail


The feto-placental endothelium in pregnancy pathologies.
MedLine Citation:
PMID:  22717877     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
This review aims to provide a comprehensive summary of the aspects of endothelial and vascular dysfunction in the feto-placental vasculature occurring in pregnancy pathologies. This endothelium is continuous with the fetal circulation. Its function and potential dysfunction in pathologies will have a profound impact on fetal development. Gestational diabetes mellitus represents one of these pathologies, in which its associated metabolic derangements will alter feto-placental endothelial functions. These, in turn, may result in functional changes of the placenta, which may entail impaired fetal development. By contrast, changes in the feto-placental vasculature observed in cases of fetal growth restriction and preeclampsia may be causative (fetal growth restriction) or secondary (preeclampsia) for the pathology.
Authors:
Christian Wadsack; Gernot Desoye; Ursula Hiden
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Publication Detail:
Type:  JOURNAL ARTICLE    
Journal Detail:
Title:  Wiener medizinische Wochenschrift (1946)     Volume:  162     ISSN:  1563-258X     ISO Abbreviation:  -     Publication Date:  2012 May 
Date Detail:
Created Date:  2012-6-21     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8708475     Medline TA:  Wien Med Wochenschr     Country:  -    
Other Details:
Languages:  ENG     Pagination:  220-224     Citation Subset:  -    
Affiliation:
Department of Obstetrics and Gynaecology, Medical University of Graz, Graz, Austria, christian.wadsack@medunigraz.at.
Vernacular Title:
Veränderungen des feto-plazentaren Endothels bei Schwangerschaftspathologien.
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