| The fetal hypothalamus and pituitary in the initiation of labour. | |
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MedLine Citation:
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PMID: 205396 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Evidence is presented for a number of events in the fetal hypothalamic-pituitary axis which may play a key role in the onset of labour: (1) In the sheep fetus a progressive rise in the fetal circulating concentrations of corticotropin in the days preceding delivery; (2) In the human fetus a switch from the production of corticotropin-like fragments (melanotropin and corticotropin-like intermediate lobe peptide) to authentic corticotropin in the last weeks of gestation; there is evidence also for a placental origin of corticotropin; (3) In the human fetus, a release of oxytocin and vasopressin associated with the process of spontaneous labour. |
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Authors:
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R Chard; R E Silman; L H Rees |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Ciba Foundation symposium Volume: - ISSN: 0300-5208 ISO Abbreviation: Ciba Found. Symp. Publication Date: 1977 |
Date Detail:
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Created Date: 1978-06-28 Completed Date: 1978-06-28 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0356636 Medline TA: Ciba Found Symp Country: NETHERLANDS |
Other Details:
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Languages: eng Pagination: 359-78 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adrenocorticotropic Hormone
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metabolism Animals Female Fetus / metabolism* Humans Hydrocortisone / metabolism Hypothalamo-Hypophyseal System / embryology Hypothalamus / embryology Labor, Obstetric* Neurophysins / metabolism Oxytocin / metabolism Pituitary Gland, Posterior / embryology* Pituitary-Adrenal System / embryology* Pregnancy Radioimmunoassay Vasopressins / metabolism |
| Chemical | |
Reg. No./Substance:
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0/Neurophysins; 11000-17-2/Vasopressins; 50-23-7/Hydrocortisone; 50-56-6/Oxytocin; 9002-60-2/Adrenocorticotropic Hormone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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